Infertility can be caused by a variety of factors in both the male and female reproductive systems. However, explaining the causes of infertility is not always possible. Infertility in the female reproductive system can be caused by: tubal disorders such as blocked fallopian tubes, which are caused by untreated sexually transmitted infections (STIs) or complications of unsafe abortion, postpartum sepsis, or abdominal/pelvic surgery; uterine disorders that can be inflammatory in nature (such as endometriosis), congenital in nature (such as the septate uterus), or benign in nature (such as fibroids). The hypothalamus and pituitary glands are part of the endocrine system. Pituitary cancers and hypopituitarism are two common disorders affecting this system.

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